Vimseltinib
Vimseltinib (DCC-3014) is a potent small molecule inhibitor targeting c-FMS (CSF-1R) and c-Kit with IC50 values of <0.01 μM and 0.1-1 μM, respectively. It is utilized in research exploring tumor-associated macrophages and has demonstrated activity in both in vitro cellular assays and in vivo models of tenosynovial giant cell tumor.
Product Specifications
CAS Number
1628606-05-2
Product Name Alternative
Inhibit, DCC 3014, DCC3014, DCC-3014, Inhibitor, colony stimulating factor 1 receptor, CD117, cFms, c-Fms, c-FMS/CSF-IR, c-Kit, cKit, CSF-1 receptor, CSF1R, CSF-1R, Vimseltinib, SCFR
Field of Research
Signal Transduction
Purity
98.98% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.65 mM) ; DMSO:60 mg/mL (139.05 mM)
Smiles
CC (C) Nc1ncc (-c2ccc (Oc3ccnc (c3) -c3cnn (C) c3) c (C) n2) c (=O) n1C
Molecular Formula
C23H25N7O2
Molecular Weight
431.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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