Amphotericin B
Amphotericin B is a broad-spectrum polyene antifungal that acts by irreversibly binding to ergosterol, thereby disrupting fungal membrane integrity. It is widely used in both in vitro susceptibility testing and in vivo models of systemic fungal infections such as aspergillosis and candidiasis.
Product Specifications
CAS Number
1397-89-3
Product Name Alternative
NSC 527017
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
>90%
Bioactivity
Antifungal agent
Form
Powder
Solubility
Soluble in DMSO (up to 18 mg/ml)
Smiles
[H][C@]12C[C@@H] (O[C@@H]3O[C@H] (C) [C@@H] (O) [C@H] (N) [C@@H]3O) \C=C\C=C\C=C/C=C/C=C/C=C/C=C/[C@H] (C) [C@@H] (O) [C@@H] (C) [C@H] (C) OC (=O) C[C@H] (O) C[C@H] (O) CC[C@@H] (O) [C@H] (O) C[C@H] (O) C[C@] (O) (C[C@H] (O) [C@H]1C (O) =O) O2
Molecular Formula
C47H73NO17
Molecular Weight
924.1
Storage Conditions
-20°C / protect from light
Notes
For research use only.
Available Sizes
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