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Amphotericin B

Amphotericin B is a broad-spectrum polyene antifungal that acts by irreversibly binding to ergosterol, thereby disrupting fungal membrane integrity. It is widely used in both in vitro susceptibility testing and in vivo models of systemic fungal infections such as aspergillosis and candidiasis.

Product Specifications

CAS Number

1397-89-3

Product Name Alternative

NSC 527017

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery

Purity

>90%

Bioactivity

Antifungal agent

Form

Powder

Solubility

Soluble in DMSO (up to 18 mg/ml)

Smiles

[H][C@]12C[C@@H] (O[C@@H]3O[C@H] (C) [C@@H] (O) [C@H] (N) [C@@H]3O) \C=C\C=C\C=C/C=C/C=C/C=C/C=C/[C@H] (C) [C@@H] (O) [C@@H] (C) [C@H] (C) OC (=O) C[C@H] (O) C[C@H] (O) CC[C@@H] (O) [C@H] (O) C[C@H] (O) C[C@] (O) (C[C@H] (O) [C@H]1C (O) =O) O2

Molecular Formula

C47H73NO17

Molecular Weight

924.1

Storage Conditions

-20°C / protect from light

Notes

For research use only.

Available Sizes

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