Pyrimethamine
Pyrimethamine (Pirimecidan) is a competitive DHFR inhibitor employed as an antimalarial agent. It is widely used in parasitology and microbiology research for studying folate metabolism, both in vitro and in models of Plasmodium infection.
Product Specifications
CAS Number
58-14-0
Product Name Alternative
Pyrimethamine, Pirimecidan, Pirimetamin, RP 4753, RP4753, RP-4753, inhibit, nucleoprotein metabolism, Parasite, parasites, folic–folinic acid systems, Inhibitor, antimalarial, Antifolate, DHFR, cell division
Field of Research
Cell Biology, Infectious Disease & Virology, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.67% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.04 mM) ; Ethanol:2.5 mg/mL (10.05 mM) ; DMSO:15.03 mg/mL (60.43 mM)
Smiles
C (C) C=1C (=C (N) N=C (N) N1) C2=CC=C (Cl) C=C2
Molecular Formula
C12H13ClN4
Molecular Weight
248.71
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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