Diphylline

Diphylline (Diprophylline) is a xanthine derivative bronchodilator that functions by inhibiting phosphodiesterase and antagonizing adenosine receptors, increasing intracellular cAMP to relax smooth muscle. It is applied in research models of asthma, COPD, and related pulmonary diseases for investigating bronchial relaxation and cAMP-mediated pathways in vitro and in vivo.

Product Specifications

CAS Number

479-18-5

Product Name Alternative

Diprophylline, Diphylline, Dyphylline, AdenosineReceptor, Adenosine Receptor, inhibit, P1 receptor, PDE, Inhibitor, phosphodiesterase, Phosphodiesterase (PDE)

Field of Research

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

98.54% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (9.83 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:47 mg/mL (184.86 mM) ; DMSO:55 mg/mL (216.33 mM)