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Cinnarizine

Cinnarizine is a piperazine-based small molecule with dual histamine H1-receptor antagonism and calcium-channel blocking activities, leading to vasodilation and antiemetic effects. It is utilized in research on vestibular disorders and motion sickness, though its use is associated with inducing extrapyramidal symptoms like parkinsonism in clinical settings.

Product Specifications

CAS Number

298-57-7

Product Name Alternative

Dimitronal, CalciumChannel, Cinarizine, Cinnarizine, Calcium Channel, Ca2+ channels, Ca channels, H1 receptor, HistamineReceptor, Histamine Receptor, inhibit, Inhibitor, Stugeron, Stutgin

Field of Research

Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

99.76% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:6.25 mg/mL (16.96 mM)

Smiles

C (\C=C\C1=CC=CC=C1) N1CCN (CC1) C (C1=CC=CC=C1) C1=CC=CC=C1

Molecular Formula

C26H28N2

Molecular Weight

368.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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