Busulfan
Busulfan is a dimethane sulfonate-derived alkylating agent that exerts cytotoxic and immunosuppressive effects by forming reactive carbonium ions, leading to DNA cross-linking and damage. It is widely used as a myeloablative conditioning agent for bone marrow transplantation and in research to establish animal models of anemia and study DNA damage mechanisms.
Product Specifications
CAS Number
55-98-1
Product Name Alternative
Apoptosis, Busulfan, Busulphan, Crosslinker, DNA Alkylator, DNA Alkylator/Crosslinker, DNA Alkylation, DNAAlkylation, DNAAlkylator, Inhibitor, inhibit, Myleran, Sulphabutin
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.31% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:3 mg/mL (12.18 mM) ; DMSO:50 mg/mL (203 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CS (=O) (=O) OCCCCOS (C) (=O) =O
Molecular Formula
C6H14O6S2
Molecular Weight
246.30
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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