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Busulfan

Busulfan is a dimethane sulfonate-derived alkylating agent that exerts cytotoxic and immunosuppressive effects by forming reactive carbonium ions, leading to DNA cross-linking and damage. It is widely used as a myeloablative conditioning agent for bone marrow transplantation and in research to establish animal models of anemia and study DNA damage mechanisms.

Product Specifications

CAS Number

55-98-1

Product Name Alternative

Apoptosis, Busulfan, Busulphan, Crosslinker, DNA Alkylator, DNA Alkylator/Crosslinker, DNA Alkylation, DNAAlkylation, DNAAlkylator, Inhibitor, inhibit, Myleran, Sulphabutin

Field of Research

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Purity

99.31% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween-80+45% Saline:3 mg/mL (12.18 mM) ; DMSO:50 mg/mL (203 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CS (=O) (=O) OCCCCOS (C) (=O) =O

Molecular Formula

C6H14O6S2

Molecular Weight

246.30

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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