10,12-Tricosadiynoic acid
10,12-Tricosadiynoic acid is a potent, orally bioavailable inhibitor of acyl-CoA oxidase-1 (ACOX1) . It ameliorates metabolic disorders induced by high-fat diet or obesity through enhancing mitochondrial fatty acid oxidation and reducing reactive oxygen species, as demonstrated in preclinical in vivo studies.
Product Specifications
CAS Number
66990-30-5
Product Name Alternative
Fatty, Inhibitor, insulin, oxidation, mono- acylglycerol acyltransferase, mitochondrial, metabolic, inhibit, Diacylglycerol acyltransferase, Diglyceride acyltransferase, acid, Acyltransferase, acyl-CoA:cholesterol acyltransferase, acyl-CoA oxidase-1, 10,12 Tricosadiynoic acid, 10,12Tricosadiynoic acid, 10,12-Tricosadiynoic acid, SIRT1-AMPK, ROS, TCDA, TDA, triglyceride
Field of Research
Metabolism Research
Purity
99.91% (May vary between batches)
Solubility
DMSO:2.75 mg/mL (7.94 mM)
Smiles
CCCCCCCCCCC#CC#CCCCCCCCCC (O) =O
Molecular Formula
C23H38O2
Molecular Weight
346.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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