Furegrelate sodium
Furegrelate sodium (U-63557A) is an orally active, selective inhibitor of thromboxane A2 synthase, demonstrating potent activity with an IC50 of 15 nM in human platelet microsomes. It is a valuable research tool for investigating thromboxane-mediated pathways in cardiovascular, pulmonary, and thrombotic diseases, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
85666-17-7
Product Name Alternative
Coronary, antiplatelet, available, arteries, arterial, Furegrelate, Furegrelate sodium, human, hypertension, Inhibitor, inhibit, orally, platelet, pulmonary, stenosed, U-63557A, TXA2R
Field of Research
Immunology & Inflammation, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery
Purity
99.92% (May vary between batches)
Solubility
DMSO:10 mg/mL (36.33 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.63 mM)
Smiles
C1=CC (=CN=C1) CC2=CC3=C (C=C2) OC (=C3) C (=O) [O-].[Na+]
Molecular Formula
C15H10NNaO3
Molecular Weight
275.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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