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Furegrelate sodium

Furegrelate sodium (U-63557A) is an orally active, selective inhibitor of thromboxane A2 synthase, demonstrating potent activity with an IC50 of 15 nM in human platelet microsomes. It is a valuable research tool for investigating thromboxane-mediated pathways in cardiovascular, pulmonary, and thrombotic diseases, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

85666-17-7

Product Name Alternative

Coronary, antiplatelet, available, arteries, arterial, Furegrelate, Furegrelate sodium, human, hypertension, Inhibitor, inhibit, orally, platelet, pulmonary, stenosed, U-63557A, TXA2R

Field of Research

Immunology & Inflammation, Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Purity

99.92% (May vary between batches)

Solubility

DMSO:10 mg/mL (36.33 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.63 mM)

Smiles

C1=CC (=CN=C1) CC2=CC3=C (C=C2) OC (=C3) C (=O) [O-].[Na+]

Molecular Formula

C15H10NNaO3

Molecular Weight

275.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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