G-5555
G-5555 is a potent and selective small molecule inhibitor of p21-activated kinase 1 (PAK1), with Kis of 3.7 nM and 11 nM for PAK1 and PAK2, respectively. This compound is a valuable research tool for studying PAK signaling in cancer cell proliferation, invasion, and metastasis in both in vitro and in vivo models.
Product Specifications
CAS Number
1648863-90-4
Product Name Alternative
Inhibit, PAK, PAK2, PAK1, Inhibitor, G 5555, G5555, G-5555, p21 activated kinases
Field of Research
Signal Transduction
Purity
99.70% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.03 mM) ; DMSO:1 mg/mL (2.03 mM)
Smiles
CNc1ncc2cc (-c3ccc (cc3Cl) -c3cccc (C) n3) c (=O) n (C[C@H]3OC[C@H] (N) CO3) c2n1
Molecular Formula
C25H25ClN6O3
Molecular Weight
492.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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