GATA4-NKX2-5-IN-1
GATA4-NKX2-5-IN-1 is a selective inhibitor of the GATA4–NKX2-5 transcriptional synergy, with an IC50 of 3 μM, without affecting kinases regulating GATA4 phosphorylation. This compound is a valuable chemical probe for studying cardiac hypertrophy and gene regulation in both cellular and animal models of heart disease.
Product Specifications
CAS Number
544681-96-1
Product Name Alternative
Inhibit, GATA4 NKX2 5 IN 1, GATA4–NKX2-5, GATA4NKX25IN1, GATA-4-NKX2-5-IN-1, GATA4-NKX2-5-IN-1, Inhibitor
Field of Research
Immunology & Inflammation, Stem Cell & Developmental Biology
Purity
99.00% (May vary between batches)
Solubility
DMSO:65 mg/mL (186.02 mM) ;10% DMSO+90% Corn Oil:2.5 mg/mL (7.15 mM)
Smiles
C (NC1=CC=C (N (CC) CC) C=C1) (=O) C=2C (=NOC2C) C3=CC=CC=C3
Molecular Formula
C21H23N3O2
Molecular Weight
349.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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