GFB-8438
GFB-8438 is a potent, subtype-selective TRPC5 inhibitor with IC50 values of 0.18 μM (hTRPC5) and 0.29 μM (hTRPC4) . This compound is a valuable research tool for studying TRPC channel function in neurological and renal disease models, both in vitro and in vivo.
Product Specifications
CAS Number
2304549-73-1
Product Name Alternative
Acetate, deoxycorticosterone, disease, cytoskeletal, GFB 8438, GFB8438, GFB-8438, hTRPC4, hTRPC5, Inhibitor, loss, kidney, mouse, inhibit, subtype, synaptopodin, remodeling, rTRPC5, selective, podocytes, Transient receptor potential channels, TRPV Channel, TRPVChannel, TRPC5, TRPChannel, TRP Channel
Field of Research
Pharmacology & Drug Discovery
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (at least 25 mg/ml)
Smiles
FC (F) (F) c1ccccc1CN1CCN (CC1=O) c1cn[nH]c (=O) c1Cl
Molecular Formula
C16H14ClF3N4O2
Molecular Weight
386.8
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
4-Chloro-5- (3-oxo-4-[[2- (trifluoromethyl) phenyl]methyl]piperazin-1-yl) -2,3-dihydropyridazin-3-one
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