GLP-26
GLP-26 is a potent HBV capsid assembly modulator (CAM) that inhibits HBV DNA replication with an IC50 of 3 nM in vitro. It disrupts pgRNA encapsidation, leading to nucleocapsid disassembly and a >90% reduction in cccDNA levels at 1 μM, making it a valuable tool for investigating HBV lifecycle and antiviral strategies.
Product Specifications
CAS Number
2133017-36-2
Product Name Alternative
Inhibitor, Hepatitis B virus, HBV, GLP26, GLP-26, GLP 26, inhibit
Field of Research
Infectious Disease & Virology
Purity
95.84% (May vary between batches)
Solubility
DMSO:100 mg/mL (267.85 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (10.71 mM)
Smiles
Cc1c (C (=O) C (=O) NCC#C) c (C) n (C) c1C (=O) Nc1ccc (F) c (F) c1
Molecular Formula
C19H17F2N3O3
Molecular Weight
373.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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