GPI-1046
GPI-1046 is a non-antibiotic immunophilin ligand that reduces ethanol consumption in preclinical models. Its mechanism involves the upregulation of the GLT1 (EAAT2) glutamate transporter in key brain regions like the prefrontal cortex and nucleus accumbens core, making it a valuable research tool for studying addiction neurobiology.
Product Specifications
CAS Number
186452-09-5
Product Name Alternative
Inhibit, HIV, HIV Protease, HIVProtease, Inhibitor, GLT1, GPI-1046, GPI1046, GPI 1046, Human immunodeficiency virus, FK506-binding protein, FKBP
Field of Research
Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Metabolism Research, Protein Biochemistry
Purity
99.69% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.16 mM) ; DMSO:100 mg/mL (277.43 mM)
Smiles
C (C (C (CC) (C) C) =O) (=O) N1[C@H] (C (OCCCC=2C=CC=NC2) =O) CCC1
Molecular Formula
C20H28N2O4
Molecular Weight
360.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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