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GR 103691

GR 103691 is a highly potent and selective dopamine D3 receptor antagonist with a Ki of 0.4 nM, exhibiting over 100-fold selectivity for hD3 over hD4 and hD1 receptors. This compound is a valuable pharmacological tool for investigating D3 receptor function in substance use disorders and Parkinson's disease, applicable in both in vitro binding assays and in vivo behavioral models.

Product Specifications

CAS Number

162408-66-4

Product Name Alternative

Human dopamine D3 receptor, GR-103691, GR103691, GR 103691, Inhibitor, inhibit, D3, DopamineReceptor, Dopamine, Dopamine Receptor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.94% (May vary between batches)

Solubility

DMSO:4.86 mg/mL (10.01 mM)

Smiles

COc1ccccc1N1CCN (CCCCNC (=O) c2ccc (cc2) -c2ccc (cc2) C (C) =O) CC1

Molecular Formula

C30H35N3O3

Molecular Weight

485.62

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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