GRL-0617
GRL0617 is a potent, selective, and noncovalent inhibitor targeting SARS-CoV-2 PLpro, exhibiting competitive inhibition with an IC50 of 0.6 μM and a Ki of 0.49 μM. This compound serves as a valuable chemical probe for studying coronavirus protease function, deubiquitinase activity, and viral replication mechanisms in both in vitro and cell-based assays.
Product Specifications
CAS Number
1093070-16-6
Product Name Alternative
Field of Research
Cell Biology, Infectious Disease & Virology, Molecular Biology, Protein Biochemistry
Purity
>99%
Bioactivity
SARS-CoV-2 papain-like protease (PLpro, Nsp3) inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 30 mg/ml) or Ethanol (up to 15 mg/ml)
Smiles
C[C@@H] (NC (=O) c1cc (N) ccc1C) c1cccc2ccccc12
Molecular Formula
C20H20N2O
Molecular Weight
304.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5-Amino-2-methyl-N- (1R-naphthalen-1-yl-ethyl) benzamide
Available Sizes
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