GSK-3β inhibitor 1
This potent and selective GSK-3β inhibitor exhibits an IC50 of 4.9 nM. It is a valuable research tool for studying glycogen metabolism, Wnt/β-catenin signaling, and diabetes mechanisms in cellular models, and has demonstrated significant anti-hyperglycemic effects in preclinical in vivo studies.
Product Specifications
CAS Number
187325-53-7
Product Name Alternative
Glycogen synthase kinase-3, Glycogen synthase kinase 3, GSK-3β inhibitor 1, GSK 3β inhibitor 1, GSK-3, GSK3, GSK-3β, GSK3β inhibitor 1, GSK-3beta inhibitor 1, GSK-3b inhibitor 1, Inhibitor, inhibit
Field of Research
Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
99.08% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9 mM) ; DMSO:30 mg/mL (134.99 mM)
Smiles
C (=C\1/C=2C (NC1=O) =CC=CC2) \C3=CC=CC=N3
Molecular Formula
C14H10N2O
Molecular Weight
222.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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