Olumacostat glasaretil
Product Specifications
UNSPSC Description
Olumacostat glasaretil (DRM01) is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC).
Target Antigen
Acetyl-CoA Carboxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Olumacostat_glasaretil.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(OCCCCCCCCCCCCCC)O1)OCC(N(CC(OCC)=O)C)=O
Molecular Weight
481.62
References & Citations
[1]Hunt DW, et al. Inhibition of Sebum Production with the Acetyl Coenzyme A Carboxylase Inhibitor OlumacostatGlasaretil. J Invest Dermatol. 2017 Mar 1. pii: S0022-202X(17)30186-0.|[2]Bissonnette R, et al. Olumacostat glasaretil, a novel topical sebum inhibitor, in the treatment of acne vulgaris: A phase IIa, multicenter, randomized, vehicle-controlled study. J Am Acad Dermatol. 2017 Jan;76(1):33-39.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-17641/Olumacostat-glasaretil-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-17641/Olumacostat-glasaretil-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1261491-89-7
Available Sizes
Curated Selection
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