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GSK2643943A

GSK2643943A is a potent and selective deubiquitylating enzyme (DUB) inhibitor targeting USP20 with an IC50 of 160 nM. It exhibits anti-tumor activity and is a valuable chemical probe for researching ubiquitin signaling in cancer biology, both in cellular and in vivo models.

Product Specifications

CAS Number

2449301-27-1

Product Name Alternative

GSK2643943A, GSK-2643943A, DUB, USP20/Ub-Rho

Field of Research

Cell Biology, Molecular Biology, Protein Biochemistry

Purity

97.09% (May vary between batches)

Solubility

DMSO:125 mg/mL (450.78 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.42 mM)

Smiles

Nc1[nH]c2cc (\C=C\c3cccc (F) c3) ccc2c1C#N

Molecular Formula

C17H12FN3

Molecular Weight

277.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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