GSK2643943A
GSK2643943A is a potent and selective deubiquitylating enzyme (DUB) inhibitor targeting USP20 with an IC50 of 160 nM. It exhibits anti-tumor activity and is a valuable chemical probe for researching ubiquitin signaling in cancer biology, both in cellular and in vivo models.
Product Specifications
CAS Number
2449301-27-1
Product Name Alternative
GSK2643943A, GSK-2643943A, DUB, USP20/Ub-Rho
Field of Research
Cell Biology, Molecular Biology, Protein Biochemistry
Purity
97.09% (May vary between batches)
Solubility
DMSO:125 mg/mL (450.78 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (14.42 mM)
Smiles
Nc1[nH]c2cc (\C=C\c3cccc (F) c3) ccc2c1C#N
Molecular Formula
C17H12FN3
Molecular Weight
277.3
Storage Conditions
-20°C
Notes
For research use only.
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