GSK2983559 free acid
GSK2983559 free acid is a potent and selective RIP2 kinase inhibitor. It effectively blocks proinflammatory cytokine production, as demonstrated in human inflammatory bowel disease explant models, supporting its utility for in vitro and in vivo research on NOD2 signaling and inflammatory pathologies.
Product Specifications
CAS Number
1579965-12-0
Product Name Alternative
Receptor-interacting protein kinases, THP-1 cell, RIPK, RIPkinase, RIP kinase, RIP2, GSK 2983559, GSK2983559, GSK-2983559, GSK2983559 free acid, GSK-2983559 free acid, inhibit, Inhibitor
Field of Research
Cell Biology, Signal Transduction
Purity
97.87% (May vary between batches)
Solubility
DMSO:4.5 mg/mL (8.36 mM)
Smiles
N (C=1C2=C (C=C (OCCOP (=O) (O) O) C (S (C (C) (C) C) (=O) =O) =C2) N=CN1) C=3C=C4C (=CC3) SC=N4
Molecular Formula
C21H23N4O7PS2
Molecular Weight
538.53
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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