Gut restricted-7
GR-7 is a covalent, orally active pan-bile salt hydrolase (BSH) inhibitor. It effectively reduces gut bacterial BSH activity, leading to decreased fecal deconjugated bile acid levels in mice, making it a valuable tool for researching microbiome-host metabolism interactions in vivo.
Product Specifications
CAS Number
2553218-46-3
Product Name Alternative
PotassiumChannel, Potassium Channel, GR7, GR-7, GR 7, Gut restricted 7, Gut restricted7, Gut restricted-7, gut-restricted, gut, Nontoxic, inhibit, Inhibitor, orally, acid, Bacterial, bile, Bile salt hydrolase (BSH), BSH
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
98.81% (May vary between batches)
Solubility
H2O:100 mg/mL (195.83 mM) ; DMSO:250 mg/mL (489.58 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.79 mM)
Smiles
O[C@H]1[C@]2 ([H]) [C@@] (CC[C@]3 ([C@@]2 ([H]) CC[C@]3 ([H]) [C@H] (C) CCC (CF) =O) C) ([H]) [C@@]4 ([C@] (C[C@@H] (CC4) OS (=O) ([O-]) =O) ([H]) C1) C.[Na+]
Molecular Formula
C25H40FNaO6S
Molecular Weight
510.64
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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