GV-58
GV-58 is a selective agonist of N- and P/Q-type voltage-gated calcium channels, with EC50 values of 7.21 μM and 8.81 μM, respectively, while exhibiting minimal activity against CDK kinases. This compound is a valuable research tool for investigating calcium channel function and neurotransmission in both cellular and animal models of neurological disorders.
Product Specifications
CAS Number
1402821-41-3
Product Name Alternative
P-Q-type Ca2+ channel, Calcium Channel, Ca2+ channels, Ca channels, CalciumChannel, GV 58, GV58, GV-58, Inhibitor, inhibit, N- and P/Q-type Ca2+ channels, N-type Ca2+ channel
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
97.36% (May vary between batches)
Solubility
DMSO:90 mg/mL (240.32 mM) ; Methanol:55 mg/mL (146.86 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (8.81 mM)
Smiles
CCCn1cnc2c (NCc3ccc (C) s3) nc (N[C@H] (CC) CO) nc12
Molecular Formula
C18H26N6OS
Molecular Weight
374.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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