Hck-IN-1
Hck-IN-1 is a selective small molecule antagonist of the HIV-1 Nef protein, potently inhibiting the Nef:Hck interaction and wild-type HIV-1 replication in vitro. It serves as a valuable chemical probe for studying Nef-dependent signaling in host cells and viral pathogenesis, with applications in retrovirology and antiretroviral drug discovery research.
Product Specifications
CAS Number
1473404-51-1
Product Name Alternative
Anti-retroviral, Asn126, diphenylpyrazolo, Human immunodeficiency virus, HIV, HIV Protease, HIV-1 Nef, HIVProtease, Hck, Hck IN 1, HckIN1, Hck-IN-1, Inhibitor, inhibit, Nef, Nef:Hck, Nef-dependent, Src, replication
Field of Research
Cardiovascular Research, Infectious Disease & Virology, Protein Biochemistry, Signal Transduction
Purity
98.29% (May vary between batches)
Solubility
DMSO:12.5 mg/mL (31.03 mM)
Smiles
NC (=S) n1nc (c (\N=N\c2cccc (Cl) c2) c1O) -c1ccc (cc1) [N+] ([O-]) =O
Molecular Formula
C16H11ClN6O3S
Molecular Weight
402.81
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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