IAXO-102
IAXO-102 is a small molecule TLR4 antagonist that suppresses downstream signaling, including MAPK and NF-κB activation, to reduce proinflammatory protein expression. It has demonstrated efficacy in preclinical models, such as inhibiting the development of abdominal aortic aneurysms in vivo.
Product Specifications
CAS Number
1115270-63-7
Product Name Alternative
Inhibit, Inhibitor, IAXO 102, IAXO102, IAXO-102, Toll-like Receptor (TLR), TLR, TLR4
Field of Research
Immunology & Inflammation
Purity
≥98% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:45 mg/mL (76.8 mM)
Smiles
CCCCCCCCCCCCCCO[C@H]1[C@H] (O) [C@@H] (CN) O[C@H] (OC) [C@@H]1OCCCCCCCCCCCCCC
Molecular Formula
C35H71NO5
Molecular Weight
585.94
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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