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Ibiglustat (L-Malic acid)

Ibiglustat L-Malic acid is a brain-penetrant, allosteric glucosylceramide synthase inhibitor. Its research applications include investigating substrate reduction therapy (SRT) for lysosomal storage disorders like Gaucher and Fabry disease, as well as exploring its neuroprotective potential in models of Parkinson's disease.

Product Specifications

CAS Number

1629063-78-0

Product Name Alternative

GZ 402671, GZ402671, GZ-402671, GZ402671 (L-Malic acid), glucosylceramide synthase, Glucosylceramide synthase, Ibiglustat L-Malic acid, Ibiglustat, L-Malic acid, SAR402671, SAR-402671, SAR402671 (L-Malic acid), SAR 402671, Venglustat, Venglustat (L-Malic acid)

Field of Research

Metabolism Research

Purity

99.54% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.3 mM) ; DMSO:90 mg/mL (171.9 mM)

Smiles

O[C@@H] (CC (O) =O) C (O) =O.CC (C) (NC (=O) O[C@@H]1CN2CCC1CC2) c1csc (n1) -c1ccc (F) cc1

Molecular Formula

C24H30FN3O7S

Molecular Weight

523.57

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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