IBR2
IBR2 is a specific RAD51 inhibitor that disrupts RAD51 multimerization and promotes its proteasomal degradation, thereby suppressing homologous recombination repair. This compound inhibits cancer cell proliferation and induces apoptosis, making it a valuable tool for studying DNA repair mechanisms in cancer research, both in vitro and in vivo.
Product Specifications
CAS Number
313526-24-8
Product Name Alternative
Apoptosis, DNA Synthesis, DNASynthesis, Inhibitor, IBR 2, IBR2, IBR-2, inhibit, Isoquinoline, RAD51, RNA Synthesis, RNASynthesis
Field of Research
Cell Biology, Molecular Biology
Purity
96.15% (May vary between batches)
Solubility
DMSO:100 mg/mL (249.69 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.99 mM)
Smiles
O=S (=O) (Cc1ccccc1) N1C=Cc2ccccc2C1c1c[nH]c2ccccc12
Molecular Formula
C24H20N2O2S
Molecular Weight
400.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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