ICI 118,551 hydrochloride
ICI 118,551 hydrochloride is a potent and highly selective β2-adrenergic receptor antagonist, with Kis of 0.7 nM for β2, 49.5 nM for β1, and 611 nM for β3 receptors. It is widely used in pharmacological research to investigate β2-AR function in both in vitro binding assays and in vivo models of asthma and cardiovascular physiology.
Product Specifications
CAS Number
72795-01-8
Product Name Alternative
Beta Receptor, Adrenergic Receptor, AdrenergicReceptor, ICI 118,551, ICI 118,551 hydrochloride, ICI 118,551 Hydrochloride, ICI 118551, ICI 118551 hydrochloride, ICI 118551 Hydrochloride, ICI118551, ICI-118551, ICI118551 Hydrochloride, ICI-118551 Hydrochloride, Inhibitor, inhibit, β3 receptor, β3-adrenergic receptor, β1 receptor, β1-adrenergic receptor, β2 receptor, β2-adrenergic receptor
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
H2O:11.11 mg/mL (35.4 mM) ; DMSO:20 mg/mL (63.72 mM) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (6.37 mM)
Smiles
Cl.CC (C) N[C@@H] (C) [C@@H] (O) COc1ccc (C) c2CCCc12
Molecular Formula
C17H28ClNO2
Molecular Weight
313.86
Storage Conditions
-20°C
Notes
For research use only.
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