IFSP1
IFSP1 is a potent and selective FSP1 (AIFM2) inhibitor with an EC50 of 103 nM, functioning independently of glutathione. It sensitizes cancer cells to ferroptosis inducers like RSL3 and uniquely induces ferroptosis in GPX4-knockout, FSP1-overexpressing cells, making it a valuable tool for investigating ferroptosis pathways in vitro.
Product Specifications
CAS Number
150651-39-1
Product Name Alternative
Cancer, A549, cell, inhibit, NCl-H1437, Inhibitor, iFSP 1, iFSP1, iFSP-1, Ferroptosis, Gpx4-knockout, FSP1-knockout, FSP1, SW620, RSL3, U-373
Field of Research
Cell Biology, Immunology & Inflammation
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to 6 mg/ml)
Smiles
Cc1ccc (cc1) -c1c (C#N) c (N) n2c3ccccc3nc2c1C#N
Molecular Formula
C20H13N5
Molecular Weight
323.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-Amino-3- (4-methylphenyl) -pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile
Available Sizes
Frequently Asked Questions
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