INH154
INH154 is a potent small molecule inhibitor targeting the Nek2-Hec1 interaction, exhibiting IC50 values of 120 nM in MB468 cells and 200 nM in Hela cells. It serves as a valuable research tool for studying mitotic regulation and has been utilized in both in vitro and in vivo cancer model studies to investigate potential anti-tumor mechanisms.
Product Specifications
CAS Number
1587705-63-2
Product Name Alternative
Inhibit, INH, INH 154, INH154, INH-154, INH in Hela cells, INH in MB468 cells, Inhibitor
Field of Research
Signal Transduction
Purity
99.57% (May vary between batches)
Solubility
H2O:< 0.1 mg/mL (insoluble) ; DMSO:65 mg/mL (165.6 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (12.74 mM)
Smiles
Cc1cc (cc (C) c1-c1csc (NC (=O) c2ccncc2) n1) N1CCCCC1
Molecular Formula
C22H24N4OS
Molecular Weight
392.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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