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Desonide

Desonide (Prednacinolone) is a synthetic topical glucocorticoid that exerts anti-inflammatory effects by activating glucocorticoid receptors. This activation modulates gene transcription, leading to the production of proteins like lipocortin-1 that inhibit key inflammatory pathways. It is widely used in research models, both in vitro and in vivo, to study steroid-mediated inflammation and immune responses.

Product Specifications

CAS Number

638-94-8

Product Name Alternative

Inhibitor, GlucocorticoidReceptor, Glucocorticoid Receptor, Locapred, inhibit, Desonide, Tridesilon, Prednacinolone

Field of Research

Cell Biology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Purity

99.29% (May vary between batches)

Solubility

Ethanol:28 mg/mL (67.23 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (6 mM) ; DMSO:55 mg/mL (132.05 mM)

Smiles

[H][C@@]12C[C@@]3 ([H]) [C@]4 ([H]) CCC5=CC (=O) C=C[C@]5 (C) [C@@]4 ([H]) [C@@H] (O) C[C@]3 (C) [C@@]1 (OC (C) (C) O2) C (=O) CO

Molecular Formula

C24H32O6

Molecular Weight

416.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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