ITI-214
ITI-214 is a highly potent and selective picomolar inhibitor of PDE1 (Ki = 58 pM), demonstrating minimal off-target activity. This tool compound is valuable for investigating PDE1's role in neurological and cardiovascular research, with utility in both cellular assays and animal models.
Product Specifications
CAS Number
1642303-38-5
Product Name Alternative
Cognitive, CNS-active, PDE, PDE1, oral, inhibit, ITI214, ITI-214, ITI 214, motor, Inhibitor, selective, phosphodiesterase, Phosphodiesterase (PDE)
Field of Research
Metabolism Research
Purity
98.21% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.3 mM) ; DMSO:30 mg/mL (49.54 mM)
Smiles
O=C (C1=C (NC2=CC=CC=C2) N (CC3=CC=C (C4=NC (F) =CC=C4) C=C3) N=C1N56) N (C) C5=N[C@@]7 ([H]) [C@]6 ([H]) CCC7.O=P (O) (O) O
Molecular Formula
C29H29FN7O5P
Molecular Weight
605.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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