Ivachtin
Ivachtin (Caspase-3 Inhibitor VII) is a potent, reversible, and noncompetitive small-molecule inhibitor of caspase-3 (IC50=23 nM) with lower activity against other caspases. This cell-permeable compound is widely used in vitro to study apoptotic pathways and has been applied in vivo within animal models of neurological and liver diseases.
Product Specifications
CAS Number
745046-84-8
Product Name Alternative
Apoptosis, caspases, Caspase-3, Caspase-3 Inhibitor VII, Caspase, modest, inhibit, Ivachtin, nonpeptide, noncompetitive, Inhibitor, selectivity, reversibl, staurosporininduced
Field of Research
Cell Biology, Protein Biochemistry
Purity
98.17% (May vary between batches)
Solubility
DMSO:slightly soluble; DMF:2 mg/mL (4.47 mM)
Smiles
O=C1C=2C=3C (N=C (C) C2C (=O) N1CCOC (C) =O) =CC=C (S (=O) (=O) N4CCOCC4) C3
Molecular Formula
C20H21N3O7S
Molecular Weight
447.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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