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JNJ-37822681 dihydrochloride

JNJ-37822681 dihydrochloride is a fast-dissociating, highly selective dopamine D2 receptor antagonist with moderate affinity (Ki = 158 nM for D2L) . This profile makes it a useful research tool for investigating D2 receptor function in neuropsychiatric disorders, applicable in both in vitro binding assays and in vivo behavioral studies.

Product Specifications

CAS Number

2108806-02-4

Product Name Alternative

D-amphetamine, D2, DopamineReceptor, Dopamine Receptor, dopamine D2, bipolar disorder, apomorphine, inhibit, JNJ 37822681, JNJ 37822681 Dihydrochloride, JNJ 37822681 dihydrochloride, JNJ37822681 dihydrochloride, JNJ-37822681 Dihydrochloride, JNJ37822681, JNJ-37822681, JNJ37822681 Dihydrochloride, Inhibitor, phencyclidine, schizophrenia

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.13% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.49 mM) ; DMSO:70 mg/mL (157.21 mM)

Smiles

Cl.Cl.Fc1ccc (CN2CCC (CC2) Nc2ccc (nn2) C (F) (F) F) cc1F

Molecular Formula

C17H19Cl2F5N4

Molecular Weight

445.26

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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