JNJ-39758979
JNJ-39758979 is a potent and selective histamine H4 receptor antagonist, with high affinity for human, mouse, and monkey receptors. It has been utilized in preclinical research to investigate the role of H4R in inflammation, allergy, and pruritus, both in vitro and in animal models.
Product Specifications
CAS Number
1046447-90-8
Product Name Alternative
Mouse H4 Receptor, histamine, Histamine Receptor, HistamineReceptor, Inhibitor, Human H4 Receptor, H4 receptor, Guinea pig H4 receptor, oral, Monkey H4 receptor, JNJ39758979, JNJ-39758979, JNJ 39758979, inhibit, cAMP, antipruritic, anti-inflammatory, agranulocytosis, Rat H4 receptor, toxicity, selective
Field of Research
Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Solubility
DMSO:55 mg/mL (248.53 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (14.91 mM)
Smiles
CC (C) c1cc (nc (N) n1) N1CC[C@@H] (N) C1
Molecular Formula
C11H19N5
Molecular Weight
221.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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