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JNJ-39758979

JNJ-39758979 is a potent and selective histamine H4 receptor antagonist, with high affinity for human, mouse, and monkey receptors. It has been utilized in preclinical research to investigate the role of H4R in inflammation, allergy, and pruritus, both in vitro and in animal models.

Product Specifications

CAS Number

1046447-90-8

Product Name Alternative

Mouse H4 Receptor, histamine, Histamine Receptor, HistamineReceptor, Inhibitor, Human H4 Receptor, H4 receptor, Guinea pig H4 receptor, oral, Monkey H4 receptor, JNJ39758979, JNJ-39758979, JNJ 39758979, inhibit, cAMP, antipruritic, anti-inflammatory, agranulocytosis, Rat H4 receptor, toxicity, selective

Field of Research

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Purity

98.00% (May vary between batches)

Solubility

DMSO:55 mg/mL (248.53 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (14.91 mM)

Smiles

CC (C) c1cc (nc (N) n1) N1CC[C@@H] (N) C1

Molecular Formula

C11H19N5

Molecular Weight

221.3

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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