JR-AB2-011
JR-AB2-011 is a potent and selective mTORC2 inhibitor (IC50 = 0.36 μM) that acts by disrupting the Rictor-mTOR interaction (Ki = 0.19 μM) . It demonstrates cytotoxic effects in glioblastoma cell models, making it a valuable research tool for studying mTORC2 signaling in cancer biology, both in vitro and in vivo.
Product Specifications
CAS Number
2411853-34-2
Product Name Alternative
JR AB2 011, JRAB2011, JR-AB-2-011, JR-AB2-011, mTORC2
Field of Research
Immunology & Inflammation, Signal Transduction
Purity
98.33% (May vary between batches)
Solubility
DMSO:61.5 mg/mL (154.41 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.02 mM)
Smiles
CC1CN (C (=O) Nc2ccc (Cl) c (Cl) c2) \C (S1) =N\c1ccc (F) cc1
Molecular Formula
C17H14Cl2FN3OS
Molecular Weight
398.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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