Topotecan HCl
Topotecan hydrochloride (NSC 609699) is a small molecule topoisomerase I inhibitor used as an antineoplastic agent. It is applied in ovarian cancer research and has been extensively studied in both in vitro cytotoxicity assays and in vivo xenograft models.
Product Specifications
CAS Number
119413-54-6
Product Name Alternative
NSC 609669; SKF-104864A
Field of Research
Cell Biology, Molecular Biology, Pharmacology & Drug Discovery
Purity
>98%
Bioactivity
Topoisomerase I inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) or in Water (up to 50 mg/ml) .
Smiles
Cl.CC[C@@]1 (O) C (=O) OCc2c1cc1-c3nc4ccc (O) c (CN (C) C) c4cc3Cn1c2=O
Molecular Formula
C23H23N3O5 • HCl
Molecular Weight
457.9
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
10-[ (Dimethylamino) methyl]-4S-ethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14 (4H,12H) -dione, HCl
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