Lanraplenib
Lanraplenib (GS-9876) is a potent and selective oral inhibitor of spleen tyrosine kinase (SYK) with an IC50 of 9.5 nM. It is being developed for inflammatory diseases and has been shown to inhibit SYK in platelet GPVI signaling without affecting bleeding time in preclinical and clinical studies.
Product Specifications
CAS Number
1800046-95-0
Product Name Alternative
Syk, SYK, Spleen tyrosine kinase, inhibit, Lanraplenib, Inhibitor, GS9876, GS-9876, GS 9876
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.35% (May vary between batches)
Solubility
DMSO:41.67 mg/mL (93.96 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.51 mM)
Smiles
Nc1cncc (n1) -c1cn2ccnc2c (Nc2ccc (cc2) N2CCN (CC2) C2COC2) n1
Molecular Formula
C23H25N9O
Molecular Weight
443.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RC211933L3V 200 µL
SLC7A3 (NM_032803) Human Tagged ORF Clone Lentiviral Particle
Sign In for Pricing
View Details abx491449-01 96 Tests
Dog High Mobility Group Protein B1 (HMGB1) CLIA Kit
Sign In for Pricing
View Details abx491449-02 5x 96 Tests
Dog High Mobility Group Protein B1 (HMGB1) CLIA Kit
Sign In for Pricing
View Details abx491449-03 10x 96 Tests
Dog High Mobility Group Protein B1 (HMGB1) CLIA Kit
Sign In for Pricing
View Details