LDN-27219
LDN-27219 is a highly effective small molecule inhibitor of human tissue transglutaminase (hTGase), exhibiting an IC50 value of 0.6 μM. This compound is a valuable research tool for investigating the role of transglutaminase activity in various disease models, including celiac disease and fibrosis, in both cellular and biochemical studies.
Product Specifications
CAS Number
312946-37-5
Product Name Alternative
HTGase, LDN27219, LDN-27219, LDN 27219, Inhibitor, inhibit, arterial pressure, smooth muscle cell, slow-binding, reversible, rat, vasodilation
Field of Research
Protein Biochemistry
Purity
99.01% (May vary between batches)
Solubility
DMSO:100 mg/mL (244.8 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (9.79 mM)
Smiles
NNC (=O) CSc1nc2scc (-c3ccccc3) c2c (=O) n1-c1ccccc1
Molecular Formula
C20H16N4O2S2
Molecular Weight
408.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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