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LIT-001

LIT-001 is a novel, nonpeptide oxytocin receptor agonist (Ki = 226 nM, EC50 = 55 nM) shown to enhance social interaction in a murine autism model. This small molecule tool compound is valuable for in vitro binding assays and in vivo behavioral studies investigating oxytocin pathway function in neuropsychiatric research.

Product Specifications

CAS Number

2245072-21-1

Product Name Alternative

Spectrum, social, OXTR, OxytocinReceptor, oxytocin receptor, Oxytocin Receptor, OT-R, receptor, V1a, vasopressin, interaction, nonbiased, Inhibitor, nonpeptide, LIT001, LIT-001, LIT 001, inhibit, autism, disorders

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

96.88% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.74 mM) ; DMSO:247 mg/mL (382.53 mM)

Smiles

OC (=O) C (F) (F) F.CN (C) C (=S) [C@@H]1CCCN1C (=O) NCc1ccc (cc1C) C (=O) N1Cc2cnn (C) c2Nc2ccccc12

Molecular Formula

C30H34F3N7O4S

Molecular Weight

645.7

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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