LIT-001
LIT-001 is a novel, nonpeptide oxytocin receptor agonist (Ki = 226 nM, EC50 = 55 nM) shown to enhance social interaction in a murine autism model. This small molecule tool compound is valuable for in vitro binding assays and in vivo behavioral studies investigating oxytocin pathway function in neuropsychiatric research.
Product Specifications
CAS Number
2245072-21-1
Product Name Alternative
Spectrum, social, OXTR, OxytocinReceptor, oxytocin receptor, Oxytocin Receptor, OT-R, receptor, V1a, vasopressin, interaction, nonbiased, Inhibitor, nonpeptide, LIT001, LIT-001, LIT 001, inhibit, autism, disorders
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
96.88% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.74 mM) ; DMSO:247 mg/mL (382.53 mM)
Smiles
OC (=O) C (F) (F) F.CN (C) C (=S) [C@@H]1CCCN1C (=O) NCc1ccc (cc1C) C (=O) N1Cc2cnn (C) c2Nc2ccccc12
Molecular Formula
C30H34F3N7O4S
Molecular Weight
645.7
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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