Bifonazole
Bifonazole (Bay H-4502) is an antifungal agent that inhibits fungal cytochrome P450 14α-demethylase (CYP51), disrupting ergosterol biosynthesis and compromising membrane integrity, leading to cell lysis. It is widely used in biochemical research to study antifungal mechanisms and has been utilized in both in vitro susceptibility assays and in vivo models of dermatophyte infections.
Product Specifications
CAS Number
60628-96-8
Product Name Alternative
Bifonazole, Bay H 4502, Bay H4502, Bay H-4502, Antibiotic, CYP51, Inhibitor, Fungal, inhibit
Field of Research
Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.29% (May vary between batches)
Solubility
Ethanol:16 mg/mL (51.55 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:1.55 mg/mL (4.99 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.22 mM)
Smiles
C (C1=CC=C (C=C1) C2=CC=CC=C2) (N3C=CN=C3) C4=CC=CC=C4
Molecular Formula
C22H18N2
Molecular Weight
310.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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