Lidocaine
Lidocaine (Alphacaine) is an amide-type local anesthetic that also demonstrates anti-inflammatory properties in both in vitro and in vivo studies. Its mechanism may involve attenuating ICAM-1 expression, reducing pro-inflammatory cytokines, and limiting neutrophil influx, making it a useful research tool in inflammation and immunology studies.
Product Specifications
CAS Number
137-58-6
Product Name Alternative
Alphacaine, Apoptosis, NF-κB, NF-kB, NFkB, NFκB, Nuclear factor-κB, Nuclear factor-kappaB, Mitogen-activated protein kinase kinase, Na channels, Na+ channels, Lignocaine, Lidocaine, inhibit, Histamine Receptor, HistamineReceptor, MEK, MAPKK, MAP2K, Inhibitor, H1 receptor, Extracellular signal regulated kinases, ERK, SodiumChannel, Sodium Channel, Xylocaine
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.35% (May vary between batches)
Solubility
DMSO:50 mg/mL (213.37 mM) ; H2O:21.34 mM;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.53 mM)
Smiles
N (C (CN (CC) CC) =O) C1=C (C) C=CC=C1C
Molecular Formula
C14H22N2O
Molecular Weight
234.34
Storage Conditions
-20°C
Notes
For research use only.
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