Doxofylline
Doxofylline is a 7-dioxolane-substituted methylxanthine used in asthma research. It demonstrates bronchodilatory efficacy comparable to theophylline in both in vitro and in vivo studies, while exhibiting an improved safety profile with fewer adverse effects such as central nervous system stimulation.
Product Specifications
CAS Number
69975-86-6
Product Name Alternative
Bronchospasm, bronchitis, BM cells, asthma, AdenosineReceptor, Adenosine Receptor, 16HBE cells, Doxofylline, Doxophylline, COPD, PDE, inhibit, Inhibitor, P1 receptor, phosphodiesterase, Phosphodiesterase (PDE), Reactive Oxygen Species
Field of Research
Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.09% (May vary between batches)
Solubility
DMSO:50 mg/mL (187.79 mM) ; H2O:22 mg/mL (82.63 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.51 mM) ; Ethanol:2 mg/mL (7.51 mM)
Smiles
Cn1c2ncn (CC3OCCO3) c2c (=O) n (C) c1=O
Molecular Formula
C11H14N4O4
Molecular Weight
266.25
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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