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Irinotecan HCl

Irinotecan hydrochloride trihydrate (CPT-11 HCl Trihydrate) is a topoisomerase I inhibitor that stabilizes the DNA-enzyme complex, preventing DNA religation and causing lethal double-strand breaks. It is widely used in cancer research for studying chemotherapy mechanisms and efficacy in both cellular and animal models.

Product Specifications

CAS Number

136572-09-3

Product Name Alternative

Topo I, Topoisomerase, Autophagy, (+) -Irinotecan hydrochloride, CPT-11 hydrochloride, CPT-11 HCl, CPT-11 HCl Trihydrate, inhibit, Irinotecan HCl, Irinotecan HCl Trihydrate, Irinotecan hydrochloride, Irinotecan Hydrochloride, Irinotecan hydrochloride trihydrate, Irinotecan hydrochloride Trihydrate, Inhibitor

Field of Research

Cell Biology

Purity

>98%

Bioactivity

Topoisomerase I inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 50 mg/ml), in Water (up to 4 mg/ml) or in Ethanol (up to 4 mg/ml) .

Smiles

O.O.O.Cl.CCc1c2Cn3c (cc4c (COC (=O) [C@]4 (O) CC) c3=O) -c2nc2ccc (OC (=O) N3CCC (CC3) N3CCCCC3) cc12

Molecular Formula

C33H38N4O6 ∙ HCl ∙ 3H20

Molecular Weight

586.69 ∙ 36.46 ∙ 54.05

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

(S) -4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3’,4’:6,7]-indolizino[1,2-b]quinolin-9-yl-[1,4’-bipiperidine]-1’-carboxylate hydrochloride

Available Sizes

Frequently Asked Questions

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