Cav 2.2 blocker 1
This small molecule is a potent and selective blocker of the N-type voltage-gated calcium channel Cav2.2 (IC50 = 1 nM) . It is a valuable research tool for investigating pain pathways and has demonstrated analgesic efficacy in preclinical in vivo models of neuropathic and inflammatory pain.
Product Specifications
CAS Number
1567335-29-8
Product Name Alternative
CalciumChannel, Cav 2.2, Cav 2.2 blocker 1, Calcium Channel, Ca channels, Ca2+ channels, inhibit, Inhibitor
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
99.38% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.71 mM) ; DMSO:20 mg/mL (47.06 mM)
Smiles
COc1ccccc1-n1nc (cc1-c1ccc (Cl) cc1) C1CC (C) (C) OC (C) (C) C1
Molecular Formula
C25H29ClN2O2
Molecular Weight
424.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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