CB-6644
CB-6644 is a potent and selective small molecule inhibitor of the RUVBL1/2 complex ATPase activity, exhibiting an IC50 of 15 nM. It is a valuable chemical probe for investigating the roles of RUVBL1/2 in cancer biology, chromatin remodeling, and c-Myc signaling in both cellular and animal models.
Product Specifications
CAS Number
2316817-88-4
Product Name Alternative
Inhibit, Inhibitor, CB6644, CB-6644, CB 6644, RUVBL1/2
Field of Research
Cell Biology, Molecular Biology
Purity
96.33% (May vary between batches)
Solubility
DMSO:49 mg/mL (85.51 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.75 mM)
Smiles
CCOc1cc (F) c (Cl) cc1C (=O) NCC (C) (C) CC (=O) Nc1c (COC) n2CCCc3ccccc3-n2c1=O
Molecular Formula
C29H34ClFN4O5
Molecular Weight
573.06
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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